Forced oscillation technique (FOT) is an emerging endpoint in asthma, COPD and other respiratory clinical trials. This non-invasive technique superimposes a multi-frequency airwave on top of a patient’s normal breathing to assess airway resistance and other lung function parameters.
Join Professor Salman Siddiqui and ERT to review:
- How oscillometry is conducted in clinical trials, and what the measurements tell us
- Potential application of FOT in particular indications (asthma, COPD and interstitial lung disease)
- Delivery of FOT in early phase clinical trials – including a biologic case study in type 2 asthma
- Sample size estimation for FOT endpoints in clinical trials
- How to best apply FOT in your next respiratory protocol
Professor Salman Siddiqui is a clinical professor of respiratory medicine and airways disease at the University of Leicester and NIHR Biomedical Research Centre. He leads the Leicester NIHR Respiratory BRC theme for phenotyping and biomarkers, is on the steering board for the international ATLANTIS small airway program.