Estimand Framework: What is it and Why You Need it in Your Clinical Trial

If you’re not using estimands in your protocols, you should be!

The objective of the estimand framework is “to align the clinical study objective with the study design, endpoint, and analysis to improve study planning and the interpretation of analysis.”

This article explores the November 2019 ICH E9 guidance addressing statistical methods for use in clinical trials, which outlined a structured statistical framework based on the use of estimands.

ERT_EstimandFramework_ACT_Feb 2020